MUC5AC overexpression in tear film of neonates

  title={MUC5AC overexpression in tear film of neonates},
  author={Flavio Mantelli and Eloisa Tiberi and Alessandra Micera and Alessandro Lambiase and Federica Visintini and Stefano Bonini},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
Full-term neonates produce tears normally, but neonatal tear film is modified to resist evaporation with a thick lipid layer that allows lower spontaneous blink rates. This adaptation presumably prevents drying of the ocular surface during long inter-blink periods. However, tear-film stability is not only based on the integrity of the lipid layer, but also reflects properties of the underlying mucus layer. Characteristics of the neonatal mucus tear-film layer have not yet been described. Tear… CONTINUE READING
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Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjögren syndrome.

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