MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma.

@article{Doyle2011MUC4IA,
  title={MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma.},
  author={Leona A. Doyle and Emely M{\"o}ller and Paola Dal Cin and Christopher D. M. Fletcher and Fredrik Mertens and Jason L Hornick},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 5},
  pages={733-41}
}
Low-grade fibromyxoid sarcoma (LGFMS) is a distinctive fibroblastic neoplasm that is characterized by alternating collagenous and myxoid areas, deceptively bland spindle cell morphology, a whorling architecture, and a t(7;16) translocation involving FUS and CREB3L2. Owing to variable morphology and a lack of discriminatory markers, LGFMS can be difficult to distinguish from benign mesenchymal tumors and other low-grade sarcomas. Gene expression profiling has identified differential upregulation… CONTINUE READING

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