MUC1 is a novel costimulatory molecule of human T cells and functions in an AP-1-dependent manner.

Abstract

MUC1 mucin, primarily known as an epithelial antigen, has been demonstrated to be expressed on activated human T cells. In the present study, we first examined the expression of MUC1 on different subsets of T cells (naive, effector, effector/memory). MUC1 appears to be strongly upregulated on activated CD4(+) T cells in comparison with CD8(+) T cells. The… (More)
DOI: 10.1016/j.humimm.2012.02.024

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Cite this paper

@article{Konowalchuk2012MUC1IA, title={MUC1 is a novel costimulatory molecule of human T cells and functions in an AP-1-dependent manner.}, author={Jeffrey D. Konowalchuk and Babita Agrawal}, journal={Human immunology}, year={2012}, volume={73 5}, pages={448-55} }