MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations

@article{Ozcan2015MTUS1AI,
  title={MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations},
  author={Onder Ozcan and Murat Kara and Onder Yumrutas and Esra Bozgeyik and Ibrahim Bozgeyik and Ozgur Ilhan Celik},
  journal={Tumor Biology},
  year={2015},
  volume={37},
  pages={6637-6645}
}
Deregulated microRNA (miRNA) expression has been shown to be involved in the pathogenesis of several types of cancers including colorectal cancer (CRC). Thus, determining miRNA targets of genes that play critical role in the malignant transformation is very important. Here, expression levels of tumor suppressor microtubule-associated tumor suppressor 1 (MTUS1) and its regulatory miRNAs were reported. Predicted and validated targets of MTUS1 gene was determined by a computational approach… CONTINUE READING
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