MT(1) melatonin receptor in the human retina: expression and localization.

@article{Scher2002MT1MR,
  title={MT(1) melatonin receptor in the human retina: expression and localization.},
  author={Judite Scher and Ellen Wankiewicz and Gregory M Brown and Hiroki Fujieda},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 3},
  pages={
          889-97
        }
}
PURPOSE Melatonin's function in human vision is far from understood, in part because of the lack of information on its cellular targets. Therefore, expression and localization of the MT(1) melatonin receptor in human retina was examined. METHODS Postmortem nonpathologic human eyes from nine donors were investigated, three by reverse transcription-polymerase chain reaction (RT-PCR) for MT(1) and MT(2) transcripts and six by immunocytochemistry, using a peptide-specific anti-MT(1) receptor… CONTINUE READING
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