MS characterization of multiple forms of alpha-amylase in human saliva.

  title={MS characterization of multiple forms of alpha-amylase in human saliva.},
  author={Christophe Hirtz and François Chevalier and Delphine Centeno and Val{\'e}rie Rofidal and J. Egea and Michel Rossignol and Nicolas Sommerer and D. Deville de P{\'e}ri{\`e}re},
  volume={5 17},
Alpha-amylase is a major and well-characterized component of human saliva. Recent proteomic studies suggested that this protein could be observed in more than twenty spots on 2-D gels of salivary proteins. The aim of this work was to investigate this unexpected redundancy. 2-D gel electrophoresis was combined with systematic MALDI-TOF MS analysis. More than 140 protein spots identifying the alpha-amylase were shown to constitute a stable but very complex pattern. Careful analysis of mass… CONTINUE READING


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Genetic and Post-translational Mechanisms Determining Human Amylase Isoenzyme Heterogeneity

R. C. Karn, J. D. Schulkin, A. D. Meritt, R. C. Newell
Isozymes. Genetics and Evolution • 1975
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