MRX87 family with Aristaless X dup24bp mutation and implication for polyAlanine expansions

Abstract

Cognitive impairments are heterogeneous conditions, and it is estimated that 10% may be caused by a defect of mental function genes on the X chromosome. One of those genes is Aristaless related homeobox (ARX) encoding a polyA-rich homeobox transcription factor essential for cerebral patterning and its mutations cause different neurologic disorders. We… (More)
DOI: 10.1186/1471-2350-8-25

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