MRP4/ABCC4 as a new therapeutic target: meta-analysis to determine cAMP binding sites as a tool for drug design.

Abstract

MRP4 transports multiple endogenous and exogenous substances and is critical not only for detoxification but also in the homeostasis of several signaling molecules. Its dysregulation has been reported in numerous pathological disorders, thus MRP4 appears as an attractive therapeutic target. However, the efficacy of MRP4 inhibitors is still controversial… (More)
DOI: 10.2174/0929867325666171229133259

Cite this paper

@article{Yaneff2017MRP4ABCC4AA, title={MRP4/ABCC4 as a new therapeutic target: meta-analysis to determine cAMP binding sites as a tool for drug design.}, author={Agust{\'i}n Yaneff and A. L. Ota{\~n}o Sahores and Natalia Gomez and Alejandro Carozzo and Carina Shayo and Carlos A. Davio}, journal={Current medicinal chemistry}, year={2017} }