MRI signs of multiple system atrophy preceding the clinical diagnosis: the case for an imaging-supported probable MSA diagnostic category.

@article{Mestre2016MRISO,
  title={MRI signs of multiple system atrophy preceding the clinical diagnosis: the case for an imaging-supported probable MSA diagnostic category.},
  author={Tiago A. Mestre and Amitabh Gupta and Anthony E Lang},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2016},
  volume={87 4},
  pages={443-4}
}
Multiple system atrophy (MSA) is a neurodegenerative disorder characterised by autonomic failure in the form of orthostatic hypotension, neurogenic bladder and impotence, in association with a variable combination of parkinsonism, cerebellar ataxia and pyramidal signs. MSA is divided into predominant parkinsonism (MSA-P) and cerebellar (MSA-C) forms. Current clinical diagnostic criteria for ‘probable MSA’ require prominent autonomic failure. However, it is widely recognised that these symptoms… CONTINUE READING