MRI of the hippocampus in Alzheimer's disease: sensitivity, specificity, and analysis of the incorrectly classified subjects.

@article{Laakso1998MRIOT,
  title={MRI of the hippocampus in Alzheimer's disease: sensitivity, specificity, and analysis of the incorrectly classified subjects.},
  author={Mikko P. Laakso and Hilkka Soininen and K. Partanen and Maarit Lehtovirta and Merja Hallikainen and Tuomo H{\"a}nninen and E L Helkala and P. Vainio and Paavo J. Riekkinen},
  journal={Neurobiology of aging},
  year={1998},
  volume={19 1},
  pages={23-31}
}
In this study, magnetic resonance imaging (MRI) of the hippocampus for the diagnosis of early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the area of the medial hippocampus with a 1.5 T MR imager in 160 subjects: 55 patients with probable AD according to the NINCDS-ADRDA criteria, 43 subjects fulfilling the NIMH criteria of age-associated memory impairment (AAMI), 42 cognitively normal elderly controls, and 20 controls younger than 50 years. Three methods for… CONTINUE READING
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