MRI of stroke using hyperpolarized 129Xe.

  title={MRI of stroke using hyperpolarized 129Xe.},
  author={Xin Zhou and Yanping Sun and Mary L. Mazzanti and N Henninger and Joey Mansour and Marc Fisher and Mitchell S. Albert},
  journal={NMR in biomedicine},
  volume={24 2},
Because there is no background signal from xenon in biological tissue, and because inhaled xenon is delivered to the brain by blood flow, we would expect a perfusion deficit, such as is seen in stroke, to reduce the xenon concentration in the region of the deficit. Thermal polarization yields negligible xenon signal relative to hyperpolarized xenon; therefore, hyperpolarized xenon can be used as a tracer of cerebral blood flow. Using a rat permanent right middle cerebral artery occlusion model… CONTINUE READING