MRI measurements of intracranial pressure in the upright posture: The effect of the hydrostatic pressure gradient

@article{Alperin2015MRIMO,
  title={MRI measurements of intracranial pressure in the upright posture: The effect of the hydrostatic pressure gradient},
  author={Noam Alperin and Sang H. Lee and Ahmet Murat Bagci},
  journal={Journal of Magnetic Resonance Imaging},
  year={2015},
  volume={42}
}
To add the hydrostatic component of the cerebrospinal fluid (CSF) pressure to magnetic resonance imaging (MRI)‐derived intracranial pressure (ICP) measurements in the upright posture for derivation of pressure value in a central cranial location often used in invasive ICP measurements. 
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21 Citations
Background Citations
5
Methods Citations
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21 Citations

Citation Type

Citation Type

MRI‐based assessment of acute effect of head‐down tilt position on intracranial hemodynamics and hydrodynamics
TLDR
To quantify the acute effect of the head‐down tilt (HDT) posture on intracranial hemodynamics and hydrodynamics, a large number of animals were fitted with EMTs for the first time.
Role of the spinal canal compliance in regulating posture‐related cerebrospinal fluid hydrodynamics in humans
TLDR
The MR‐ICP and the craniospinal CSF SV were significantly correlated with the spinal contribution to the overall CSC, suggesting that the spinal canal plays a role in modulating ICP upon postural changes.
Quantifying the influence of respiration and cardiac pulsations on cerebrospinal fluid dynamics using real‐time phase‐contrast MRI
To validate a real‐time phase contrast magnetic resonance imaging (RT‐PCMRI) sequence in a controlled phantom model, and to quantify the relative contributions of respiration and cardiac pulsations…
Venous collapse regulates intracranial pressure in upright body positions.
TLDR
The hypothesis that postural ICP changes are governed by hydrostatic effects in the venous system and IJV collapse supports the development of better treatments for neurological and neurosurgical conditions affecting ICP.
Upright versus supine MRI: effects of body position on craniocervical CSF flow
TLDR
Body position has significant effects on CSF flow in and out of the cranium, with more CSF oscillating in supine compared to upright position, which may play a beneficial role in waste clearance in the brain.
Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging
TLDR
Assessment of pulse pressure gradient at level C2 was not found feasible to replace invasive monitoring of pulsatile intracranial pressure in selection of patients with idiopathic normal pressure hydrocephalus for surgical shunting, because of complexity of cervical cerebrospinal fluid flow and -pulsatility at the upper cervical spinal canal.
Effect of gravity on brain structure as indicated on upright computed tomography
TLDR
The intracranial structure of healthy subjects and volume of ventricles changed according to posture on Earth, and the shape of CSF spaces with changes in posture was observed.
Imaging cerebrospinal fluid dynamics in idiopathic normal pressure hydrocephalus
TLDR
The results do not support the use of aqueductal stroke volume for selecting patients for shunting, and diagnostic preoperative monitoring of MWA is used routinely and predicts a beneficial shunt response in patients with iNPH.
Review of non-invasive intracranial pressure measurement techniques for ophthalmology applications
TLDR
Although only used in small studies to date, a MRI based method known as MR-ICP appears to be the best non-invasive technique for estimating ICP, with two-depth transcranial ultrasound and ophthalmodynamometry showing potential as well.
Intracranial volumetric changes govern cerebrospinal fluid flow in the Aqueduct of Sylvius in healthy adults
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