MRI evaluation of asymmetry of nigrostriatal damage in the early stage of early-onset Parkinson's disease.

@article{Wang2015MRIEO,
  title={MRI evaluation of asymmetry of nigrostriatal damage in the early stage of early-onset Parkinson's disease.},
  author={Jianli Wang and Qing X. Yang and Xiaoyu Sun and Jeffrey Vesek and Zachary Mosher and Megha M Vasavada and Jonathan Chu and S Kanekar and Vikram Shivkumar and Kala Venkiteswaran and Thyagarajan Subramanian},
  journal={Parkinsonism & related disorders},
  year={2015},
  volume={21 6},
  pages={590-6}
}
INTRODUCTION The motor symptoms and signs of early-onset idiopathic Parkinson's disease (PD) in Hoehn and Yahr (H&Y) stage-1 are generally unilateral. We hypothesized that there would be detectable differences in the quantitative MRI parameters in these PD patients between the hemispheres contralateral to the clinically symptomatic and non-symptomatic body side. METHODS We tested this hypothesis by comparing transverse relaxation rates and diffusion tensor imaging (DTI) parameters in the… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 40 references

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

JH Kordower, CW Olanow, +3 authors CH Adler
Brain 2013;136:2419e31 • 2013

Regional alterations of brain microstructure in Parkinson's disease using diffusion tensor imaging.

Movement disorders : official journal of the Movement Disorder Society • 2012
View 2 Excerpts

Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society • 2011

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