MRI differentiation of pneumonia-like mucinous adenocarcinoma and infectious pneumonia.

Abstract

OBJECTIVE To evaluate the role of MRI water-sensitive sequences in the differential diagnosis between pneumonia-like mucinous adenocarcinoma and infectious pneumonia. SUBJECTS AND METHODS Twenty-three patients with pneumonia-like mucinous adenocarcinoma and 30 patients with infectious pneumonia underwent computed tomography (CT) and MRI. Two blinded and independent readers evaluated CT and MR images using a 3-level confidence scale in two separate sessions. Results were tested for statistical significance using the Fisher's exact test and the Cohen's k test. RESULTS On CT, the two readers respectively made correct diagnoses of mucinous adenocarcinoma in 17 out of 23 cases (73.9%), and in 15 out of 23 cases (65.2%). A correct diagnosis of infectious pneumonia was made in 22 out of 30 cases (73.3%), and in 24 out of 30 cases (80.0%). On MRI, both readers made correct diagnoses of mucinous adenocarcinoma in 23 out of 23 (100%) cases, and of infectious pneumonia in 30 out of 30 (100%) cases. Fisher's exact test showed a significant difference in the diagnosis of mucinous adenocarcinoma between MRI and CT for both readers, P=0.01 for reader 1 and P=0.002 for reader 2, respectively. A good agreement (k=0.73) was found between the two readers on CT evaluation, whereas an almost perfect agreement (k=1.00) was found for MRI. CONCLUSIONS MRI with "water-sensitive" sequences should be added in the diagnostic protocol of every patient with pulmonary consolidation suspected to be mucinous adenocarcinoma.

DOI: 10.1016/j.ejrad.2011.12.022

Cite this paper

@article{Gaeta2012MRIDO, title={MRI differentiation of pneumonia-like mucinous adenocarcinoma and infectious pneumonia.}, author={Michele Gaeta and Giorgio Ascenti and Silvio Mazziotti and Rosario Contiguglia and Mario Barone and Achille Mileto}, journal={European journal of radiology}, year={2012}, volume={81 11}, pages={3587-91} }