MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease.

@article{Dickerson2001MRIderivedEA,
  title={MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease.},
  author={Barry Dickerson and Irina Goncharova and Michael P. Sullivan and Concetta M Forchetti and Robert Smith Wilson and David A. Bennett and Laurel A Beckett and Leyla deToledo-Morrell},
  journal={Neurobiology of aging},
  year={2001},
  volume={22 5},
  pages={747-54}
}
With high resolution, quantitative magnetic resonance imaging (MRI) techniques, it is now possible to examine alterations in brain anatomy in vivo and to identify regions affected in the earliest stages of Alzheimer's disease (AD). In this study, we compared MRI-derived entorhinal and hippocampal volume in healthy elderly controls, patients who presented at the clinic with cognitive complaints, but did not meet criteria for dementia (non-demented), and patients with very mild AD. The two… CONTINUE READING
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