MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder.

  title={MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder.},
  author={James Douglas Bremner and Meena Vythilingam and Eric Vermetten and Steven M. Southwick and Thomas McGlashan and Ahsan Nazeer and Sarfraz Khan and Loredana Vaccarino and Robert Soufer and Pradeep K Garg and Chin K. Ng and Lawrence H. Staib and James S. Duncan and Dennis S. Charney},
  journal={The American journal of psychiatry},
  volume={160 5},
OBJECTIVE Animal studies have suggested that early stress is associated with alterations in the hippocampus, a brain area that plays a critical role in learning and memory. The purpose of this study was to measure both hippocampal structure and function in women with and without early childhood sexual abuse and the diagnosis of posttraumatic stress disorder (PTSD). METHOD Thirty-three women participated in this study, including women with early childhood sexual abuse and PTSD (N=10), women… 

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