MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images.

@article{Hecht2001MRIFLAIRIO,
  title={MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images.},
  author={Martin J. Hecht and Franz Fellner and Claudia Fellner and Max J Hilz and Dieter Heuss and Bernhard Neundoerfer},
  journal={Journal of the neurological sciences},
  year={2001},
  volume={186 1-2},
  pages={37-44}
}
In some patients with amyotrophic lateral sclerosis (ALS), T2-weighted and proton-density-weighted magnetic resonance imaging (MRI) shows hyperintense or hypointense signals at the corticospinal tract. Fluid-attenuated inversion recovery (FLAIR) sequences increase the sensitivity of MRI to detect cortical and subcortical tissue changes. In 31 ALS patients and 33 controls, we studied the frequency and the extent of signal abnormalities in FLAIR images compared to T2-, T1- and proton-density… CONTINUE READING
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