MR spectroscopy measurement of the diffusion of dimethyl sulfoxide in articular cartilage and comparison to theoretical predictions.

@article{Abazari2012MRSM,
  title={MR spectroscopy measurement of the diffusion of dimethyl sulfoxide in articular cartilage and comparison to theoretical predictions.},
  author={Alireza Abazari and Janet A W Elliott and Locksley E Mcgann and Russell B. Thompson},
  journal={Osteoarthritis and cartilage},
  year={2012},
  volume={20 9},
  pages={
          1004-10
        }
}
UNLABELLED Cartilage cryopreservation requires optimal loading of protective solutes, most commonly dimethyl sulfoxide (DMSO), to maximize chondrocyte survival. Previously, diffusion models have been used to predict the distribution of solutes in tissue samples, but the accuracy of spatiotemporal predictions of these models have not been validated with empirical studies and remains unknown. OBJECTIVE In this study, magnetic resonance spectroscopic imaging was used to measure the spatial and… CONTINUE READING
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