MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging.

@article{Fazekas1987MRSA,
  title={MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging.},
  author={Franz Fazekas and John B. Chawluk and Abass Alavi and Howard I. Hurtig and Robert A. Zimmerman},
  journal={AJR. American journal of roentgenology},
  year={1987},
  volume={149 2},
  pages={
          351-6
        }
}
The type, frequency, and extent of MR signal abnormalities in Alzheimer's disease and normal aging are a subject of controversy. With a 1.5-MR unit we studied 12 Alzheimer patients, four subjects suffering from multiinfarct dementia and nine age-matched controls. Punctate or early confluent high-signal abnormalities in the deep white matter, noted in 60% of both Alzheimer patients and controls, were unrelated to the presence of hypertension or other vascular risk factors. A significant number… 

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