MR microscopy of magnetically labeled neurospheres transplanted into the Lewis EAE rat brain.

@article{Bulte2003MRMO,
  title={MR microscopy of magnetically labeled neurospheres transplanted into the Lewis EAE rat brain.},
  author={Jeff W M Bulte and Tamir Ben-Hur and Bradley Robert Miller and Rachel Mizrachi-Kol and Ophira Einstein and Etti Reinhartz and Holly A Zywicke and Trevor Douglas and Joseph A. Frank},
  journal={Magnetic resonance in medicine},
  year={2003},
  volume={50 1},
  pages={
          201-5
        }
}
Stem cell transplantation is being explored as a new paradigm for the treatment of demyelinating diseases. Magnetically labeled multipotential neural precursor cells were transplanted into the ventricles of rats with acute experimental allergic encephalomyelitis (EAE) and high-resolution (microscopic) MR images were obtained ex vivo. Migration patterns of live cells into periventricular white matter structures could be easily visualized, with a good correlation of the corresponding… CONTINUE READING
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