MR lymphography using iron oxide particles. Detection of lymph node metastases in the VX2 rabbit tumor model.

@article{Taupitz1993MRLU,
  title={MR lymphography using iron oxide particles. Detection of lymph node metastases in the VX2 rabbit tumor model.},
  author={Matthias Taupitz and Susanne M. Wagner and Bernd Hamm and Dieter Dienemann and Ruediger Lawaczeck and K. J. Wolf},
  journal={Acta radiologica},
  year={1993},
  volume={34 1},
  pages={10-5}
}
MR images of the iliac lymph nodes of 25 VX2 carcinoma-bearing rabbits and of 5 tumor-free rabbits were obtained at 1.5 T before and after endolymphatic administration of superparamagnetic iron oxide particles (SPIO) at a dose of 1 mumol Fe per extremity. Imaging results were correlated with histology. In unenhanced images intranodal metastases were not detectable with any of the pulse sequences used and the signal intensities of tumor-free and metastatic lymph nodes did not differ… CONTINUE READING

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