MR lymphography: study of a high-efficiency lymphotrophic agent.

Abstract

PURPOSE To investigate the utility of a monocrystalline iron oxide nanoparticle (MION) as a contrast agent in magnetic resonance (MR) imaging of lymph nodes. MATERIALS AND METHODS Pharmacokinetic data were obtained in rats after intravenous, subcutaneous, and intraarterial injection of indium-111-MION-46. MR imaging was performed to determine optimal… (More)

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