MR guidance in radiotherapy

@article{Lagendijk2014MRGI,
  title={MR guidance in radiotherapy},
  author={Jan J. W. Lagendijk and Bas W. Raaymakers and Cornelis A. T. Van Den Berg and Marinus A. Moerland and Marielle E.P. Philippens and Marco van Vulpen},
  journal={Physics in Medicine \& Biology},
  year={2014},
  volume={59},
  pages={R349 - R369}
}
Magnetic resonance imaging (MRI) has become, over the last 30 years, one of the main pillars of modern diagnostic imaging, which is widely used for many clinical problems. One of the reasons for its success is the high level of technical innovation which has turned modernday MRI into a versatile medical imaging modality (Haacke et al 1999). MRI stands out in terms of soft tissue visualization. MRI does not require ionizing radiation. In addition, it provides several functional imaging… 
Radiotherapy planning using MRI
TLDR
The wide range of image contrast mechanisms available to MRI and the way they are exploited for RT planning are reviewed, followed by a brief discussion on the development of real-time MRI-guided RT.
Imaging science and development in modern high-precision radiotherapy
Medical physics challenges in clinical MR-guided radiotherapy
TLDR
Although several challenges exist, the intrinsic benefits of MRgRT will provide a deeper understanding of dose delivery effects on an individual basis, with the potential for further treatment personalization.
MR-Only Methodology
TLDR
The purpose of this chapter is to provide an overview of the main methods for generating substitute CT from MRI scans for MRI-only radiation therapy treatment planning.
A review of substitute CT generation for MRI-only radiation therapy
TLDR
A variety of promising approaches exist that seem clinical acceptable even with standard clinical MRI sequences, and a consistent reference frame for method benchmarking is probably necessary to move the field further towards a widespread clinical implementation.
A narrative review of MRI acquisition for MR-guided-radiotherapy in prostate cancer.
TLDR
This review attempts to give a comprehensive overview of MRI acquisition techniques currently used in the clinical workflows of PCa MRgRT, from treatment planning to online treatment guidance, in order to promote MRI practice and research for PCaMRgRT.
Functional imaging for radiotherapy treatment planning: current status and future directions—a review
  • D. Thorwarth
  • Medicine, Physics
    The British journal of radiology
  • 2015
TLDR
The current status and future directions of different clinically available functional imaging modalities; CT, MRI, positron emission tomography (PET) as well as the hybrid imaging techniques PET/CT and PET/MRI and their potential for individualized RT are discussed.
Role and future of MRI in radiation oncology.
TLDR
On-going advances in MRL technologies promise improved real time soft tissue visualization, treatment margin reductions, beam optimization, inhomogeneity corrected dose calculation, fast multileaf collimators and volumetric arc radiation therapy.
Emerging role of MRI in radiation therapy
TLDR
The emerging role of MRI in radiation dose plans and delivery is highlighted, but more so for MR‐only treatment planning and delivery.
...
...

References

SHOWING 1-10 OF 145 REFERENCES
Abdominal Magnetic Resonance Imaging at 3 T: Oncological Applications
TLDR
Progress in signal-to-noise ratio at 3 T magnetic resonance (MR) imaging has the potential of improving the accuracy of MR imaging in the detection, staging, treatment planning, and follow-up of patients with abdominal tumors.
Dedicated magnetic resonance imaging in the radiotherapy clinic.
Abdominal MRI advances in the detection of liver tumours and characterisation.
  • R. Low
  • Medicine, Biology
    The Lancet. Oncology
  • 2007
MRI/linac integration.
Real-time correction of magnetic field inhomogeneity-induced image distortions for MRI-guided conventional and proton radiotherapy
TLDR
It is argued that, although field inhomogeneities cannot be prevented from occurring, distortion correction is not always necessary in practice, and this work opens new possibilities for investigating on-line MRI-based plan adaptations and ultimately MRI- based treatment planning.
Investigation of a method for generating synthetic CT models from MRI scans of the head and neck for radiation therapy
TLDR
The presented method has the potential to generate synthetic CT images to support the workflow of radiation oncology treatment planning and image guidance, and generated MRCT and CT images showed similar contrast between bone and soft/solid tissues.
The promise of dynamic contrast-enhanced imaging in radiation therapy.
  • Yue Cao
  • Medicine, Physics
    Seminars in radiation oncology
  • 2011
MRI simulation for radiotherapy treatment planning.
  • S. Devic
  • Physics, Medicine
    Medical physics
  • 2012
TLDR
This review summarizes the efforts of incorporation of MRI data into target definition process for RTP based on gained clinical evidence so far and opens a question whether the time is up for bringing a MRI-simulator as an additional standard imaging tool into radiation oncology departments.
MRI of the lung: state of the art.
TLDR
The technical aspects and protocol suggestions for chest MRI are reviewed and the role of MRI in the evaluation of nodules and masses, airway disease, respiratory mechanics, ventilation, perfusion and hemodynamics, and pulmonary vasculature is discussed.
...
...