MR contrast due to intravascular magnetic susceptibility perturbations.

  title={MR contrast due to intravascular magnetic susceptibility perturbations.},
  author={J L Boxerman and L M Hamberg and Bruce R. Rosen and Robert M. Weisskoff},
  journal={Magnetic resonance in medicine},
  volume={34 4},
A particularly powerful paradigm for functional MR imaging of microvascular hemodynamics incorporates paramagnetic materials that create significant image contrast. These include exogenous (lanthanide chelates) and endogenous (deoxygenated hemoglobin) agents for mapping cerebral blood volume and neuronal activity, respectively. Accurate interpretation of these maps requires an understanding of the biophysics of susceptibility-based image contrast. The authors developed a novel Monte Carlo model… CONTINUE READING
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