MR Contrast Agent at High-Field MRI (3 Tesla)

@article{Trattnig2003MRCA,
  title={MR Contrast Agent at High-Field MRI (3 Tesla)},
  author={Siegfried Trattnig and Ahmed Ba-Ssalamah and Iris Melanie Noebauer-Huhmann and Markus Barth and Stefan Wolfsberger and Katja Pinker and Engelbert Knosp},
  journal={Topics in Magnetic Resonance Imaging},
  year={2003},
  volume={14},
  pages={365-375}
}
Tumor-to-brain contrast after gadolinium administration using MP-RAGE and T1-SE scans in patients with primary and secondary brain tumors was significantly higher at 3 T than at 1.5 T. The subjective assessment of cumulative triple-dose 3 Tesla images obtained the best results in the detection of brain metastases compared with other sequences followed by 1.5 T cumulative triple-dose enhanced images. In macroadenomas of the hypophysis, contrast-enhanced 3 T MRI was superior to standard MRI in… 
Brain Tumor Enhancement in MR Imaging at 3 Tesla: Comparison of SNR and CNR Gain Using TSE and GRE Techniques
TLDR
With TSE at 3 T, the SNR gain comes close to the theoretically expected doubling with an even higher tumor CNR increase, and contrast dose should not be decreased at 1.5 T.
Brain Tumor Enhancement in Magnetic Resonance Imaging: Comparison of Signal-to-Noise Ratio (SNR) and Contrast-to-Noise Ratio (CNR) at 1.5 Versus 3 Tesla
TLDR
Using a standardized animal model and matched scan techniques, this study shows a significant benefit of 3 T compared with 1.5 T in contrast-enhanced brain tumor magnetic resonance imaging.
Comparison of gd-dtpa-induced signal enhancements in rat brain c6 glioma among different pulse sequences in 3-tesla magnetic resonance imaging
TLDR
FSPGR is superior to FSE and comparable to SE in its ability to delineate rat brain C6 glioma in the thalamus region and showed significantly higher signal enhancement than F SE and comparable enhancement to SE.
Detection of brain metastasis at 3T: comparison among SE, IR-FSE and 3D-GRE sequences
TLDR
At 3T, the contrast-enhanced 3D fast SPGR with 1.4 mm isotropic voxel is clinically more valuable for detecting small brain metastases than the SE and IR-FSE with section thickness of 6 mm.
Magnetic Resonance Imaging of the Pancreas at 3.0 Tesla: Qualitative and Quantitative Comparison With 1.5 Tesla
TLDR
The results suggest that 3.0 T may offer promise for improved body MRI, although further technical development to optimize SNR and improve signal homogeneity will be needed before its full potential can be achieved.
T1-Weighted Imaging of the Brain at 3 Tesla Using a 2-Dimensional Spoiled Gradient Echo Technique
TLDR
High-quality, thin-section (3-mm) T1-weighted imaging can be readily performed at 3 T using a very short in-phase TE 2-D GRE technique and is advocated for routine brain imaging at 1.5 T.
The Efficacy of Gadobenate Dimeglumine (Gd-BOPTA) at 3 Tesla in Brain Magnetic Resonance Imaging: Comparison to 1.5 Tesla and a Standard Gadolinium Chelate Using a Rat Brain Tumor Model
TLDR
As a result of transient protein binding, Gd-BOPTA may be superior to standard gadolinium chelates in neurologic imaging at 3 T in a rat glioma model.
...
...

References

SHOWING 1-10 OF 68 REFERENCES
Magnetic Resonance Imaging Contrast Enhancement of Brain Tumors at 3 Tesla Versus 1.5 Tesla
TLDR
Administration of a gadolinium contrast agent produces higher contrast between tumor and normal brain at 3 tesla than at 1.5 tesLA, and Signal enhancement of the lesions in T1-SE sequences was not significantly different between both field strengths.
High-Resolution Three-Dimensional Contrast-Enhanced Blood Oxygenation Level-Dependent Magnetic Resonance Venography of Brain Tumors at 3 Tesla: First Clinical Experience and Comparison with 1.5 Tesla
TLDR
Acquisition of CE-MRV data at 3 T enables spatial resolution to be increased within the same measurement time and with the same volume coverage compared with 1.5 T, thus providing more detailed information.
Brain lesion contrast in MR imaging
TLDR
The contrast effect of Gd contrast media is higher at 1.5 T than at 0.3 T, and higher doses than presently used might prove useful especially at lower field strengths where the contrast effectof Gd is less pronounced.
Increased detection of intracranial metastases with intravenous Gd-DTPA.
TLDR
The detection of additional lesions with Gd-DTPA increased the radiologic suspicion of metastatic disease, revealed locations more favorable for biopsy, prompted the search for a primary tumor, and modified therapeutic objectives and methods.
High-Resolution MR Venography at 3.0 Tesla
TLDR
Investigating the visualization of small venous vessels in the normal human brain at a field strength of 3 Tesla offers the possibility of improved resolution and the delineation of smaller vessels compared with lower field strengths.
Administration of gadopentetate dimeglumine in MR imaging of intracranial tumors: dosage and field strength.
TLDR
The results confirm that 0.1 mmol/kg gadopentetate dimeglumine is more effective at enhancing intracranial tumors than lower doses at mid and high field MR units.
High‐dose gadoteridol in MR imaging of intracranial neoplasms
TLDR
High‐dose gadoteridol injection (0.3‐mmol/kg cumulative dose) provided improved lesion detection on MR images specifically in intracranial metastatic disease in patients with a high suspicion of brain metastases by previous clinical or radiologic examinations.
Gd-DTPA enhanced high resolution MR imaging of pituitary adenomas.
TLDR
The delineation of the adenoma from the cavernous sinus was improved from 47% in unenhanced scans to 91% after Gd-DTPA administration, and there was evidence of adenomas only in the enhanced images.
The effect of contrast dose, imaging time, and lesion size in the MR detection of intracerebral metastasis.
TLDR
In the evaluation of small central nervous system metastases, either delayed imaging after the injection of standard contrast dose or higher contrast dose may improve their detection, and therefore affect clinical management.
MR evaluation of CNS tumors: dose comparison study with gadopentetate dimeglumine and gadoteridol.
TLDR
Improved enhancement, detection, and delineation of central nervous system (CNS) neoplasms resulting from increased injected doses of gadoteridol have the potential to be clinically significant and may justify the possibly higher cost of increased contrast material dosage.
...
...