MR-387A and B, new aminopeptidase N inhibitors, produced by Streptomyces neyagawaensis SL-387.

@article{Chung1996MR387AAB,
  title={MR-387A and B, new aminopeptidase N inhibitors, produced by Streptomyces neyagawaensis SL-387.},
  author={M. Chung and H. Chun and K. Han and H. J. Lee and C. Lee and Y. Kho},
  journal={The Journal of antibiotics},
  year={1996},
  volume={49 1},
  pages={
          99-102
        }
}
become new drugs for cancer treatment, not as biological response modifiers (BRM), but as anti-cancer chemicals exerting direct suppressive action on the growth or metastasis of certain cancers. Thus, the specific inhibition ofAP-N could be a new approach to suppress the growth or metastasis of cancer. During the screening for new inhibitors of aminopeptidase N, we obtained new substances MR-387Aand B (Fig. 1) from the culture broth of Streptomyces neyagawaensis SL-387. In this communication… Expand
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