MPTP-induced degeneration: interference with glutamatergic toxicity.

@article{Lschmann1994MPTPinducedDI,
  title={MPTP-induced degeneration: interference with glutamatergic toxicity.},
  author={P A L{\"o}schmann and Klaus W. Lange and Helmut Wachtel and Lechoslaw Turski},
  journal={Journal of neural transmission. Supplementum},
  year={1994},
  volume={43},
  pages={133-43}
}
Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity. Although the primary cause of PD is still not known some features make this disorder a model for neurodegenerative diseases in general. It has been known for some time that symptomatic PD can be attributed to insults with symptoms occurring many years later such as post-encephalitic PD or PD following manganese poisoning. More… CONTINUE READING
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