MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.

@article{Kantardzhieva2006MPP3IR,
  title={MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.},
  author={Albena Kantardzhieva and Svetlana Alexeeva and Inge A J Versteeg and Jan Wijnholds},
  journal={The FEBS journal},
  year={2006},
  volume={273 6},
  pages={
          1152-65
        }
}
Mutations in the human Crumbs homologue 1 (CRB1) gene are a frequent cause of various forms of retinitis pigmentosa. The CRB1-membrane-associated palmitoylated protein (MPP)5 protein complex is thought to organize an intracellular protein scaffold in the retina that is involved in maintenance of photoreceptor-Müller glia cell adhesion. This study focused on the binding characteristics and subcellular localization of MPP3, a novel member of the MPP5 protein scaffold at the outer limiting… CONTINUE READING

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