MPD3: a useful medicinal plants database for drug designing

@article{Mumtaz2017MPD3AU,
  title={MPD3: a useful medicinal plants database for drug designing},
  author={A. Mumtaz and U. Ashfaq and M. T. ul Qamar and F. Anwar and F. Gulzar and M. Ali and N. Saari and M. T. Pervez},
  journal={Natural Product Research},
  year={2017},
  volume={31},
  pages={1228 - 1236}
}
Abstract Medicinal plants are the main natural pools for the discovery and development of new drugs. In the modern era of computer-aided drug designing (CADD), there is need of prompt efforts to design and construct useful database management system that allows proper data storage, retrieval and management with user-friendly interface. An inclusive database having information about classification, activity and ready-to-dock library of medicinal plant’s phytochemicals is therefore required to… Expand
Uttarakhand Medicinal Plants Database (UMPDB): A Platform for Exploring Genomic, Chemical, and Traditional Knowledge
TLDR
The primary goal of developing this database is to provide traditional, genomic, and chemical descriptions of the medicinal plants exclusively found in various regions of Uttarakhand. Expand
Biological Databases for Medicinal Plant Research
Bioinformatics resources serve as an important source of data, knowledge, and information in biological studies, including plants having medicinal properties. Most of the plants found in nature haveExpand
Evaluating new strategies for anticancer molecules from ethnic medicinal plants through in silico and biological approach - A review
TLDR
This review emphasizes the recent plant species known with anticancer properties either invitro or invivo as well as bioinformatics and computational approaches discussed for research in medicinal plants based research. Expand
Prediction of Medicinal Properties Using Mathematical Models and Computation, and Selection of Plant Materials
TLDR
This chapter presents an overview of methods and processes involved in plant selection by utilizing various mathematical modelling and computational techniques. Expand
Metabolomics of medicinal and aromatic plants: Goldmines of secondary metabolites for herbal medicine research
TLDR
The present chapter aims to provide updated and comprehensive information about secondary metabolites in MAPs, with detailed information of the latest metabolomics databases. Expand
Drug target identification and virtual screening in pursuit of phytochemical intervention of Mycobacterium chelonae
TLDR
A subtractive genomics approach is employed to predict the potential therapeutic candidates, intended for experimental research against Mycobacterium chelonae, and N-acetylglucosamine-1-phosphate uridyltransferase (GlmU) was chosen as a case study from identified therapeutic targets, based on its important bifunctional role. Expand
Web repositories of natural agents promote pests and pathogenic microbes management.
TLDR
This study surveyed databases of NPs, AMPs, medicinal plants and plant EOs with insecticidal, antibacterial, antiviral and antifungal activity, and compared their functionality, data volume, data sources and applicability and comprehensively discussed the limitation of these web resources. Expand
Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus
TLDR
Novel scaffolds against DV serotypes are brought forth to serve as lead molecules for further optimization and drug development against all DV serotype heterotypic re-infection with equal effect against multiple disease causing DV proteins. Expand
Food bioactive small molecule databases: Deep boosting for the study of food molecular behaviors
Abstract Food Bioactive Small Molecule Databases (FBSMDs) provide valuable data resources for the study of molecular behavior, molecular nutrition, as well as the R&D of drugs and health products. InExpand
Promising Terpenes as Natural Antagonists of Cancer: An In-Silico Approach
TLDR
Results found that the selected terpenes hits (3-trans-p-coumaroyl maslinic acid, Silvestrol and Betulonic acid) are potential inhibitors of p53–MDM2 interaction and could serve as potent antagonists. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 67 REFERENCES
MPDB 1.0: a medicinal plant database of Bangladesh
TLDR
MPDB 1.0 database is dedicated to provide the first window to find the plants around Bangladesh claimed to have medicinal and/or nutritive values by accumulating data from the published literatures. Expand
MAPS Database: Medicinal plant Activities, Phytochemical and Structural Database
TLDR
MAPS (Medicinal plant Activities, Phytochemicals & structural database) has been constructed with uniqueness that it combines all information in one web resource and additionally provides test targets on which particular plant found to be effective with reference to the original paper as well. Expand
MEDDB: A medicinal plant database developed with the information gathered from tribal people in and around Madurai, Tamil Nadu
TLDR
MEDDB has been developed, which stores the details of 110 plant species that are commonly used by tribes for fever, asthma, cold, cough, diabetes, diarrhea, dysentery, eye infections, stomach ache, wounds and snake bite. Expand
DrugBank: a comprehensive resource for in silico drug discovery and exploration
TLDR
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug data with comprehensive drug target information and is fully searchable supporting extensive text, sequence, chemical structure and relational query searches. Expand
Natural products in drug discovery.
  • A. Harvey
  • Computer Science, Medicine
  • Drug discovery today
  • 2008
TLDR
Various screening approaches are being developed to improve the ease with which natural products can be used in drug discovery campaigns, and data mining and virtual screening techniques are also being applied to databases of natural products. Expand
Computer-aided drug discovery and development (CADDD): in silico-chemico-biological approach.
  • I. Kapetanovic
  • Computer Science, Medicine
  • Chemico-biological interactions
  • 2008
TLDR
It is expected that the power of CADDD will grow as the technology continues to evolve. Expand
Computer Aided Screening of Phytochemicals from Garcinia against the Dengue NS2B/NS3 Protease
TLDR
It can be concluded from the study that these Gracinia phytochemicals found to be bound deeply inside the active site of DENV NS2B/NS3 protease could serve as important inhibitors to inhibit the viral replication inside the host cell. Expand
Predicting molecular interactions in silico: I. A guide to pharmacophore identification and its applications to drug design.
TLDR
A broad, yet concise guide to pharmacophore identification and a sample of applications for drug design is presented and the framework of the algorithms, classify their modules and point out their advantages and challenges are presented. Expand
Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents).
  • J. Calixto
  • Medicine
  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 2000
TLDR
The trend in the domestication, production and biotechnological studies and genetic improvement of medicinal plants will offer great advantages, since it will be possible to obtain uniform and high quality raw materials which are fundamental to the efficacy and safety of herbal drugs. Expand
...
1
2
3
4
5
...