MONALISA for stochastic simulations of Petri net models of biochemical systems

@inproceedings{Balazki2015MONALISAFS,
title={MONALISA for stochastic simulations of Petri net models of biochemical systems},
author={Pavel Balazki and Klaus Lindauer and Jens Einloft and J{\"o}rg Ackermann and Ina Koch},
booktitle={BMC Bioinformatics},
year={2015}
}

The concept of Petri nets (PN) is widely used in systems biology and allows modeling of complex biochemical systems like metabolic systems, signal transduction pathways, and gene expression networks. In particular, PN allows the topological analysis based on structural properties, which is important and useful when quantitative (kinetic) data are incomplete or unknown. Knowing the kinetic parameters, the simulation of time evolution of such models can help to study the dynamic behavior of the… CONTINUE READING