MOLECULAR SCREENING FOR PLASMODIUM FALCIPARUM RESISTANCE MARKERS FOR ARTEMISININS IN MBITA , KENYA

@inproceedings{Wangai2011MOLECULARSF,
  title={MOLECULAR SCREENING FOR PLASMODIUM FALCIPARUM RESISTANCE MARKERS FOR ARTEMISININS IN MBITA , KENYA},
  author={Laura Nyawira Wangai and Muriira Geoffrey and Sahibzada Omar and Gabriel N. Magoma and Francis Thuo Kimani and Jonathan M. Mwangi and William Marion and Burugu and Naomi Maina},
  year={2011}
}
Artemisinins-based combination therapies (ACTs) are being recommended against uncomplicated malaria in endemic areas of Africa. However, in these areas data on their long term usefulness is limited. It has been demonstrated that ACTs resistance may be due to single nucleotide polymorphisms (SNPs) in the chemotherapeutic target, the SERCA-type ATPase protein (PfATPase6). This study analyzed PfATPase6 mutations in asymptomatic infections from samples collected from Mbita, a malaria endemic region… CONTINUE READING