MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

@article{Aras2015MNRR1C,
  title={MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.},
  author={Siddhesh Aras and Minbo Bai and Icksoo Lee and Roger Springett and Maik H{\"u}ttemann and Lawrence I. Grossman},
  journal={Mitochondrion},
  year={2015},
  volume={20},
  pages={43-51}
}
Our understanding of stress-associated regulatory mechanisms for mitochondria remains incomplete. We now report a new regulator of mitochondrial metabolism, the coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) which, based on the functionality described here, is renamed MNRR1 (Mitochondria Nuclear Retrograde Regulator 1). It functions in a novel way by acting in two cellular compartments, mitochondria and nucleus. In normally growing cells most MNRR1 is located in… CONTINUE READING
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