MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase.

  title={MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase.},
  author={Ren Zhang},
  journal={Journal of cellular physiology},
  volume={230 8},
Nicotinamide adenine dinucleotide (NAD) and its phosphorylated form, NADP, play essential roles in numerous cellular processes in all organisms. NADP maintains a pool of its reducing equivalent, NADPH, which regenerates cellular oxidative defense systems to counteract oxidative damages. Mitochondria represent a major source of oxidative stress, because the majority of superoxide, a reactive oxygen species, is generated from the mitochondrial respiratory chain. Therefore, as universal electron… CONTINUE READING
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