MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms

Abstract

Identifying the functional importance of the millions of single nucleotide polymorphisms (SNPs) in the human genome is a difficult challenge. Therefore, a reverse strategy, which identifies functionally important SNPs by virtue of the bimodal abundance across the human population of the SNP-related mRNAs will be useful. Those mRNA transcripts that are… (More)
DOI: 10.1186/1471-2164-12-43

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Cite this paper

@inproceedings{Affara2010MMP1BE, title={MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms}, author={Muna Affara and Benjamin J. Dunmore and Deborah Sanders and Nicola Johnson and Cristin G. Print and David Stephen Charnock-Jones}, booktitle={BMC Genomics}, year={2010} }