MMP cellular responses to dengue virus infection-induced vascular leakage.

@article{Luplertlop2008MMPCR,
  title={MMP cellular responses to dengue virus infection-induced vascular leakage.},
  author={Natthanej Luplertlop and Doroth{\'e}e Miss{\'e}},
  journal={Japanese journal of infectious diseases},
  year={2008},
  volume={61 4},
  pages={298-301}
}
Dengue hemorrhagic fever and dengue shock syndrome, the major life-threatening outcomes of severe dengue disease, are the consequence of plasma leakage in the vascular areas. We previously demonstrated that dengue virus (DV)-infected dendritic cells (DC) trigger vascular leakage through matrix metalloproteinase (MMP)-9 overproduction, however little is known concerning the consequences of direct infection of macrovascular endothelial cells (MVEC) by DV. In this study, we show that infection of… CONTINUE READING

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