MMP-9 polymorphisms are related to serum lipids levels but not associated with colorectal cancer susceptibility in Chinese population

@article{Yang2012MMP9PA,
  title={MMP-9 polymorphisms are related to serum lipids levels but not associated with colorectal cancer susceptibility in Chinese population},
  author={Zhi-hui Yang and Shi-Ning Li and Jin-xing Liu and Q Guo and Xing-Wang Sun},
  journal={Molecular Biology Reports},
  year={2012},
  volume={39},
  pages={9399-9404}
}
Matrix metalloproteinases (MMPs) play an important role in cancer development and aggression. MMP-9 polymorphisms may affect MMPs expression and contribute to interindividual differences in susceptibility to a wide spectrum of cancers. The purpose of this study was to investigate the association of MMP-9 P574R and R668Q polymorphisms with colorectal cancer (CRC); and to explore the relationship among the polymorphisms and clinicopathologic parameters, serum tumor markers and lipids. The… CONTINUE READING

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