MMP-9 expression in meningiomas: a prognostic marker for recurrence risk?

@article{Barresi2010MMP9EI,
  title={MMP-9 expression in meningiomas: a prognostic marker for recurrence risk?},
  author={Valeria Barresi and Enrica E Vitarelli and Giovanni Tuccari and Gaetano Barresi},
  journal={Journal of Neuro-Oncology},
  year={2010},
  volume={102},
  pages={189-196}
}
Despite total macroscopic resection of meningiomas relapses do occur in these tumours, possibly because of microscopic clusters of neoplastic cells left in the dura mater or in the arachnoid membrane. The invasiveness of the neoplastic cells of human meningiomas has been related to expression of matrix-metalloproteinase-9 (MMP-9), a peptidase actively implicated in the degradation of the extracellular matrix; nonetheless, the prognostic value of MMP-9 in the risk of recurrence of meningiomas… CONTINUE READING
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