MMP-1 promoter polymorphism: association with chronic periodontitis severity in a Brazilian population.

Abstract

BACKGROUND A single nucleotide polymorphism was described in the promoter region of the human MMP-1 gene, and this polymorphism has been associated with risk of cancer metastasis and inflammatory diseases. In this paper, we studied the possible relationship between the MMP-1 promoter polymorphism and the severity of chronic periodontitis. METHODS Genomic… (More)

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