MMP‐9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma

@article{ElShabrawi2001MMP9IP,
  title={MMP‐9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma},
  author={Y. El-Shabrawi and N. Ardjomand and H. Radner},
  journal={The Journal of Pathology},
  year={2001},
  volume={194}
}
Extracellular matrix‐degrading enzymes are crucial for cancer metastases. One group of enzymes that has been increasingly implicated in the breakdown of the extracellular matrix, and hence the intravasation and dissemination of tumour cells, is the family of metalloproteinases. In the recent past, increasing efforts have led to the development of more or less specific matrix metalloproteinase (MMP) inhibitors. Data concerning the molecular nature and timing of the contribution of MMPs to tumour… Expand
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