MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi)

Abstract

Dear Editor, Mixed lineage leukemia (MLL) is characterized by abnormal MLL proteins derived from MLL gene aberrations. Importantly, it confers a poor prognosis in adults, with limited response to conventional chemotherapy [1]. We report a case of a 60-year-old man with MLL-aberrant acute myeloid leukemia, who sustained a complete cytogenetic response (CCyR… (More)
DOI: 10.1007/s00277-010-1099-6

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@article{Burbury2010MLLaberrantLC, title={MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi)}, author={Kate L. Burbury and Mark J. Bishton and Ricky W. Johnstone and Michael J. Dickinson and Jeff Szer and H. Miles Prince}, journal={Annals of Hematology}, year={2010}, volume={90}, pages={847-849} }