MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer.

@article{MuizMendoza2012MLH1AX,
  title={MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer.},
  author={R Mu{\~n}iz-Mendoza and Mar{\'i}a de la Luz Ayala-Madrigal and Miriam Partida-P{\'e}rez and Jorge Peregrina-Sandoval and Evelia Leal-Ugarte and Nelly Margarita Mac{\'i}as-G{\'o}mez and Valeria Peralta-Leal and Juan Pablo Meza-Espinoza and Jose Miguel Moreno-Ortiz and R Ram{\'i}rez-Ram{\'i}rez and S Su{\'a}rez-Villanueva and Melva Guti{\'e}rrez-Angulo},
  journal={Genetics and molecular research : GMR},
  year={2012},
  volume={11 3},
  pages={2315-20}
}
DNA repair proteins maintain DNA integrity; polymorphisms in genes coding for these proteins can increase susceptibility to colorectal cancer (CRC) development. We analyzed a possible association of MLH1 -93G>A and 655A>G and XRCC1 Arg194Trp and Arg399Gln polymorphisms with CRC in Mexican patients. Genomic DNA samples were obtained from peripheral blood of 108 individuals with CRC (study group) at diagnosis and 120 blood donors (control group) from Western Mexico; both groups were mestizos. The… CONTINUE READING
Highly Cited
This paper has 76 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

76 Citations

02040'13'15'17
Citations per Year
Semantic Scholar estimates that this publication has 76 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 30 references

MLH 193 G > A promoter polymorphism and risk of mismatch repair deficient colorectal cancer

  • JM Allan, J Shorto, J Adlard, J Bury
  • Int . J . Cancer
  • 2008
Highly Influential
2 Excerpts

EPM2AIP1 promoter activity

  • S Raptis, M Mrkonjic, RC Green, VV Pethe
  • 2007
Highly Influential
1 Excerpt

MLH 193 G > A promoter polymorphism and the risk of microsatellite - unstable colorectal cancer

  • S Raptis, M Mrkonjic, RC Green, VV Pethe
  • J . Natl . Cancer Inst
  • 2007
Highly Influential
1 Excerpt

associated with better outcome in sporadic colorectal cancer

  • XM Pan, WZ Yang, GH Xu, P Bai
  • Cancer Genet. Cytogenet
  • 2011
1 Excerpt

mismatch repair and cancer susceptibility: a meta-analysis. Mutagenesis

  • S Perera, M Mrkonjic, JB Rawson, B Bapat
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…