MK801 increases feeding and decreases drinking in nondeprived, freely feeding rats

@article{Jahng2001MK801IF,
  title={MK801 increases feeding and decreases drinking in nondeprived, freely feeding rats},
  author={Jeong Won Jahng and Thomas A. Houpt},
  journal={Pharmacology Biochemistry and Behavior},
  year={2001},
  volume={68},
  pages={181-186}
}
The noncompetitive NMDA receptor antagonist MK801 has been reported to increase food intake in rats during scheduled test meals of palatable foods or after food deprivation, but not in nondeprived rats given rodent chow. To determine if MK801 has an effect on spontaneous meals, MK801 (100 microg/kg) was administered 15 min prior to dark onset to nondeprived rats maintained on powdered rodent chow, and spontaneous food and water access was measured. MK801 increased the length of the first meal… CONTINUE READING

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