MK2 plays an important role for the increased vascular permeability that follows thermal injury.

@article{Wu2013MK2PA,
  title={MK2 plays an important role for the increased vascular permeability that follows thermal injury.},
  author={Wei Wu and Qiaobing Huang and Jingxia Miao and Mingjia Xiao and Hongxia Liu and Kesen Zhao and Ming Zhao},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2013},
  volume={39 5},
  pages={923-34}
}
We previously reported Rho kinase is involved in vessel hyper-permeability caused by burns. Here we further explore the Rho kinase downstream signaling, it is found that its specific inhibitor Y27632 significantly diminishes the activation of JNK and p38 MAPKs but not ERK that induced by serum from burned rats (burn-serum). JNK activation was found involved… CONTINUE READING