MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic Stress

Abstract

The integrity of the intestinal epithelium is crucial for the barrier function of the gut. Replenishment of the gut epithelium by intestinal stem cells contributes to gut homeostasis, but how the differentiated enterocytes are protected against stressors is less well understood. Here we use the Drosophila larval hindgut as a model system in which damaged… (More)
DOI: 10.1371/journal.pgen.1002168

Topics

6 Figures and Tables

Cite this paper

@inproceedings{Seisenbacher2011MK2DependentPS, title={MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic Stress}, author={Gerhard Seisenbacher and Ernst Hafen and Hugo Stocker}, booktitle={PLoS genetics}, year={2011} }