MK-801 prevents the enhanced behavioural response to apomorphine elicited by repeated electroconvulsive treatment in mice

Abstract

Repeated administration of electroconvulsive stimuli (ECS) to mice once daily for a period of 7 days results in an enhanced locomotor response induced by apomorphine (1.0 mg/kg, IP). Pretreatment (30 min) with the N-methyl-d-aspartate (NMDA) receptor antagonist, MK-801 (0.01–1.0 mg/kg IP), suppressed ECS-induced seizure activity in a dose-dependent manner… (More)
DOI: 10.1007/BF02245125

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@article{Nomikos1992MK801PT, title={MK-801 prevents the enhanced behavioural response to apomorphine elicited by repeated electroconvulsive treatment in mice}, author={George Nomikos and A. A. Math{\'e} and J{\'e}r{\^o}me Math{\'e} and Tobias Svensson}, journal={Psychopharmacology}, year={1992}, volume={108}, pages={367-370} }