MIP-la and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Thl / 1 h 2 lymphoctye differentiation

Abstract

Chemokines are a family of small-molecularweight cytokines that induce chemotaxis and chemokinesis of leukocytes. These molecules are ligands for seven-transmembrane, G-protein-hinked receptors and are known to activate integrins on the surface of leukocytes and other cells as well as induce a number of signaling events. They play a significant role in the… (More)

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