MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4.

@article{Ramos2005MIP1alphaCCL3AO,
  title={MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4.},
  author={Cleber Douglas Lucinio Ramos and Cl{\'a}udio Azevedo Canetti and Janeusa T Souto and Jo{\~a}o S. Silva and Cory M Hogaboam and S{\'e}rgio Henrique Ferreira and Fernando Queiroz Cunha},
  journal={Journal of leukocyte biology},
  year={2005},
  volume={78 1},
  pages={167-77}
}
In the present study, we investigated the involvement of macrophage-inflammatory protein-1alpha (MIP-1alpha)[CC chemokine ligand 3 (CCL3)], MIP-1beta[CCL4], regulated on activation, normal T expressed and secreted (RANTES)[CCL5], and CC chemokine receptors (CCRs) on neutrophil migration in murine immune inflammation. Previously, we showed that ovalbumin (OVA)-triggered neutrophil migration in immunized mice depends on the sequential release of tumor necrosis factor alpha (TNF-alpha) and… CONTINUE READING