MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells.

Abstract

Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long noncoding RNAs (lncRNAs), on MYC ability to influence the cellular transcriptome. Here, we have intersected RNA-sequencing data from two MYC-inducible cell lines and a cohort of 91 B-cell lymphomas… (More)
DOI: 10.1073/pnas.1505753112

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@article{Doose2015MINCRIA, title={MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells.}, author={Gero Doose and Andrea Haake and Stephan H. Bernhart and Cristina L{\'o}pez and Sujitha Duggimpudi and Franziska Wojciech and Anke K. Bergmann and Arndt Borkhardt and Birgit Burkhardt and Alexander Claviez and Lora Dimitrova and Siegfried Haas and Jessica I. Hoell and Michael Hummel and Dennis Karsch and Wolfram Klapper and Karsten Kleo and Helene Kretzmer and Markus Kreuz and Ralf K{\"{u}ppers and Chris Lawerenz and Dido Lenze and Markus L{\"{o}ffler and Luisa Mantovani-Loeffler and Peter DR Moeller and German Ott and Julia Richter and Marius Rohde and Philip Rosenstiel and Andreas Rosenwald and M. Schilhabel and Markus Schneider and Ingrid Scholz and Stephan Stilgenbauer and Hendrik G. Stunnenberg and M. Szczepanowski and Lorenz H. Tr{\"{u}mper and Marc Andr{\'e}e Weniger and Steve Hoffmann and Reiner Siebert and Ingram Iaccarino}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2015}, volume={112 38}, pages={E5261-70} }