MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans.

@article{Masuda2012MIG13CA,
  title={MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans.},
  author={Hitomi Masuda and Kuniaki Nakamura and Nozomu Takata and Bunsho Itoh and Takashi Hirose and Hiroki Moribe and Eisuke Mekada and M Okada},
  journal={FEBS letters},
  year={2012},
  volume={586 6},
  pages={740-6}
}
The transmembrane protein MIG-13 is a key regulator required for anterior migration of neural cells in Caenorhabditis elegans, but the signaling mechanisms involved remain unknown. Here, we isolated a suppressor mutation in the unc-71/adm-1 gene, which rescued the AVM neuron migration defect in mig-13 mutants. Genetic analyses revealed that UNC-71 at least… CONTINUE READING