MIF produced by bone marrow-derived macrophages contributes to teratoma progression after embryonic stem cell transplantation.

@article{Wang2012MIFPB,
  title={MIF produced by bone marrow-derived macrophages contributes to teratoma progression after embryonic stem cell transplantation.},
  author={Xiaofei Wang and Tianxiang Chen and Lin Leng and Jianqing Fan and Kai Cao and Zhaoxia Duan and Xi-Jing Zhang and Changshun Shao and M. Wu and Iman Tadmori and Tian-yi Li and Li Liang and Dongming Sun and Shu-sen Zheng and Andreas Meinhardt and Wise Young and Richard Bucala and Yi Ren},
  journal={Cancer research},
  year={2012},
  volume={72 11},
  pages={
          2867-78
        }
}
  • Xiaofei Wang, Tianxiang Chen, +15 authors Yi Ren
  • Published in Cancer research 2012
  • Biology, Medicine
  • Although stem cell therapy holds promise as a potential treatment in a number of diseases, the tumorigenicity of embryonic stem cells (ESC) and induced pluripotent stem cells remains a major obstacle. In vitro predifferentiation of ESCs can help prevent the risk of teratoma formation, yet proliferating neural progenitors can generate tumors, especially in the presence of immunosuppressive therapy. In this study, we investigated the effects of the microenvironment on stem cell growth and… CONTINUE READING

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    Citations

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    Anti-Inflammatory Mechanism of Neural Stem Cell Transplantation in Spinal Cord Injury

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